Research by the Perelman School of Medicine clearly shows that the brain's ability to respond to insulin, which is important for normal brain function, is going offline at some point. Insulin in the brain not only modulates glucose uptake, but also promotes the health of brain cells — their growth, survival, remodelling, and normal functioning.
Brain Insulin Resistance Contributes to Cognitive Decline in Alzheimer's Disease
Relationship between Alzheimers disease and diabetes - Diabetes Type III
A lot of research has been looking at any correlation between type II diabetes and Alzheimer’s disease. Research has shown that there may indeed be a relationship. Alzheimer’s disease is a neurodegenerative disease where things called amyloid beta plaques and tau tangles build up in the brain, causing neurons to die and leading to impaired memory and cognitive dysfunction. Due to the decrease in insulin within the brain, or the increase in insulin resistance, insulin is unable to properly carry out its functions. This can lead to Tau hyperphosphorylation and neurofibrillary tangles along with amyloid beta plaque formation, all of which lead to death of brain cells. Understanding the causes and consequences of tau dysfunction is an important priority of dementia research.
The figure below shows how both type 1 and type II diabetes can lead to Alzheimer’s disease.
What is so unfortunate about this relationship between Alzheimers disease and Type II diabetes is that with the increase in diabetes in places where a western life style is adopted there will also be an enormous increase in Alzheimers disease in the future. The chances of someone getting Alzheimers increases as we get older, and with suffering type II diabetes, the risk of developing AD increases by 50%. The question is how do we help prevent AD, or even diabetes ?
What are the true keys to helping battle diabetes, preventing diabetes, and lowering the chances of getting AD? They are a healthy diet, exercise, good sleep, learning how to reduce stress, fasting overnight for 12+ hours and education. Exercise not only helps with blood sugar, but also is healthy for our whole body. Not having enough restful sleep increases the demand on stress hormones and drains energy.
Brain Insulin Resistance Contributes to Cognitive Decline in Alzheimer's Disease
Relationship between Alzheimers disease and diabetes - Diabetes Type III
A lot of research has been looking at any correlation between type II diabetes and Alzheimer’s disease. Research has shown that there may indeed be a relationship. Alzheimer’s disease is a neurodegenerative disease where things called amyloid beta plaques and tau tangles build up in the brain, causing neurons to die and leading to impaired memory and cognitive dysfunction. Due to the decrease in insulin within the brain, or the increase in insulin resistance, insulin is unable to properly carry out its functions. This can lead to Tau hyperphosphorylation and neurofibrillary tangles along with amyloid beta plaque formation, all of which lead to death of brain cells. Understanding the causes and consequences of tau dysfunction is an important priority of dementia research.
The figure below shows how both type 1 and type II diabetes can lead to Alzheimer’s disease.
What is so unfortunate about this relationship between Alzheimers disease and Type II diabetes is that with the increase in diabetes in places where a western life style is adopted there will also be an enormous increase in Alzheimers disease in the future. The chances of someone getting Alzheimers increases as we get older, and with suffering type II diabetes, the risk of developing AD increases by 50%. The question is how do we help prevent AD, or even diabetes ?
What are the true keys to helping battle diabetes, preventing diabetes, and lowering the chances of getting AD? They are a healthy diet, exercise, good sleep, learning how to reduce stress, fasting overnight for 12+ hours and education. Exercise not only helps with blood sugar, but also is healthy for our whole body. Not having enough restful sleep increases the demand on stress hormones and drains energy.